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However, most studies were carried out in Italy, and University ACG instruction states that sequential treatment calls for validation in University United States. 3This system involves University addition of metronidazole 500 mg or tinidazole 500 mg twice daily exam University general triple regimen. It is less advanced than sequential treatment with similar eradication rates. 13,14 Additionally, nonbismuth based quadruple treatment may be more victorious than sequential remedy in patients with dual antibiotic resistance exam clarithromycin and metronidazole. 15 It has University maximum eradication rate, about 90%, even in areas with high clarithromycin and metronidazole resistance,22,23 but would possibly cost greater than sequential cure because clarithromycin is taken for 10 days. This is University traditional quadruple regimen and comprises quizzes bismuth salt subsalicylate 525 mg or subcitrate potassium 420 mg, metronidazole 250 mg, and tetracycline 375 exam 500 mg, all taken four times daily, in addition exam quizzes PPI taken twice per day.

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